研究成果(Selected publication, SCI)
   2022年度 研究成果
Tsai HJ, Yang AC, Tsai SJ, Ma Y, Kuo TBJ, Yang CCH, Peng CK. Associations of Reduced Sympathetic Neural Activity and Elevated Baroreflex Sensitivity With Non-Rapid Eye Movement Sleep: Evidence From Electroencephalogram- and Electrocardiogram-Based Sleep Staging. Psychosom Med. 2022 Jun 1;84(5):621-631.
Su VY, Chou KT*, Tseng CH, Kuo CY, Su KC, Perng DW, Chen YM, Chang SC. Mouth opening/breathing is common in sleep apnea and linked to more nocturnal water loss. Biomed J. 2022 May 9:S2319-4170(22)00073-7.
Tsai HJ, Yang AC, Zhu JD, Hsu YY, Hsu TF, Tsai SJ. Effectiveness of Digital Cognitive Behavioral Therapy for Insomnia in Young People: Preliminary Findings from Systematic Review and Meta-Analysis. J Pers Med. 2022 Mar 16;12(3):481
Chou KT, Tsai YL, Yeh WY, Chen YM, Huang N, Cheng HM. * Risk of work-related injury in workers with obstructive sleep apnea: A systematic review and meta-analysis. J Sleep Res. 2022 Feb;31(1):e13446.
   2021年度 研究成果
Hou SJ, Tsai SJ, Kuo PH, Lin WY, Liu YL, Yang AC, Lin E, Lan TH. An association study in the Taiwan Biobank elicits the GABAA receptor genes GABRB3, GABRA5, and GABRG3 as candidate loci for sleep duration in the Taiwanese population. BMC Med Genomics. 2021 Sep 16;14(1):223
Liu GR, Lin TY, Wu HT, Sheu YC, Liu CL, Liu WT, Yang MC, Ni YL, Chou KT, Chen CH, Wu D, Lan CC, Chiu KL, Chiu HY, Lo YL. Using an Interpretable Machine Learning Algorithm. J Clin Sleep Med. 2021 Feb 1;17(2):159-166. Large Scale Assessment of Consistency in Sleep Stage Scoring Rules among Multiple Sleep Centers J Clin Sleep Med. 2021 Feb 1;17(2):159-166.
Tsai HJ, Kuo TBJ, Yang AC, Tsai SJ, Yang CCH. Difficulty in initiating sleep is associated with poor morning cardiovascular function. Psychiatry Res. 2021 Jan;295:113518.
   2020年度 研究成果
Ho CN, Fu PH, Chen JY, Hung KC, Chang JH, Peng CK, Yang AC.* Heart rate variability and surgical pleth index under anesthesia in poor and normal sleepers. J Clin Monit Comput. 2020 Dec;34(6):1311-1319.
Lin CY, Tsai SJ, Peng CK, Yang AC.* Sleep state instabilities in patients with periodic limb movements in sleep - Detection and quantification with heart rate variability. Psychiatry Res. 2020 Nov;293:113454.
Hou SJ, Tsai SJ, Kuo PH, Liu YL, Yang AC, Lin E, Lan TH. An association study in the Taiwan Biobank reveals RORA as a novel locus for sleep duration in the Taiwanese Population. Sleep Med. 2020 Sep;73:70-75.
   2019年度 研究成果
Chou KT, Cheng SC, Huang SF, Perng DW, Chang SC, Chen YM, Hsu HS, Hung SC.* Impact of Intermittent Hypoxia on Sepsis Outcomes in a Murine Model. Sci Rep. 2019 Sep 9;9(1):12900.
   2018年度 研究成果
Chou KT*, Chang SC, Shiao TH. The Earliest Development of Sleep Medicine And Research in Taiwan. Sleep Biol Rhythms. 2018: 16(2), 259-260.
Ma Y, Yeung A, Yang AC, Peng CK, Clain A, Alpert J, Fava M, Yeung AS. The Effects of Tai Chi on Sleep Quality in Chinese American Patients With Major Depressive Disorder: A Pilot Study. Behav Sleep Med. 2018 Jul-Aug;16(4):398-411.
Ma Y, Shi W, Peng CK, Yang AC.* Nonlinear dynamical analysis of sleep electroencephalography using fractal and entropy approaches. Sleep Med Rev. 2018 Feb;37:85-93
   2017年度 研究成果
Hsiao YH, Chen YT, Tseng CM, Wu LA, Perng DW, Chen YM, Chen TJ, Chang SC, Chou KT*. Sleep disorders and an increased risk of Parkinson's disease in individuals with non-apnea sleep disorders: a population-based cohort study. J Sleep Res. 2017 Oct;26(5):623-628.
Chiang CL, Chen YT, Wang KL, Su VY, Wu LA, Perng DW, Chang SC, Chen YM, Chen TJ, Chou KT*. Comorbidities and risk of mortality in patients with sleep apnea. Ann Med. 2017 Aug;49(5):377-383.
Lin WC, Shen CC, Tsai SJ, Yang AC*. Increased Risk of Myofascial Pain Syndrome Among Patients with Insomnia. Pain Med. 2017 Aug 1;18(8):1557-1565.
   2016年度 研究成果
Chu H, Shih CJ, Ou SM, Chou KT, Lo YH, Chen YT. Association of sleep apnoea with chronic kidney disease in a large cohort from Taiwan. Respirology. 2016 May;21(4):754-60.
   2015年度 研究成果
Tseng CM, Chen YT, Tao CW, Ou SM, Hsiao YH, Li SY, Chen TJ, Perng DW, Chou KT*. Adult narcoleptic patients have increased risk of cancer: A nationwide population-based study. Cancer Epidemiol. 2015 Dec;39(6):793-7.
Su VY, Chen YT, Lin WC, Wu LA, Chang SC, Perng DW, Su WJ, Chen YM, Chen TJ, Lee YC, Chou KT*. Sleep Apnea and Risk of Panic Disorder. Ann Fam Med. 2015 Jul-Aug;13(4):325-30.
Ma Y, Dong M, Mita C, Sune S, Peng CK, Yang AC*. Publication analysis on insomnia: how much has been done in the past two decades. Sleep Med. 2015 Jul;16(7):820-6.
Hsiao YH, Chen YT,Tseng CM, Wu LA,Lin WC, Su VY, Perng DW , Chang SC, Chen YM, Chen TJ, Lee YC, Chou KT*. Sleep Disorders and Increased Risk of Autoimmune Diseases in Individuals without Sleep Apnea. Sleep. 2015 Apr 1;38(4):581-6. 
Chi JC, Chiang RP*, Chou TY, Shu CH, Shiao AS, Lin CM. The role of lateral pharyngoplasty in obstructive sleep apnea syndrome. Eur Arch Otorhinolaryngol. 2015 Feb;272(2):489-96.
   2014年度 研究成果
Tseng CH, Lin FC, Chao HS, Tsai HC, Shiao GM, Chang SC*. Impact of rapid ascent to high altitude on sleep. Sleep Breath. 2014 Dec 10. [Epub ahead of print]
Chou KT, Liu CC, Hsu HS, Chang SC, Chen YM, Perng DW, Hsu YT, Lee YC, Hung SC*. Nocturnal stem cell mobilization in patients with obstructive sleep apnoea: a pilot study. Eur J Clin Invest. 2014 Dec;44(12):1189-96.
Tsai PJ, Chen SC, Hsu CY, Wu CW, Wu YC, Hung CS, Yang AC, Liu PY, Biswal B, Lin CP. Local awakening: Regional reorganizations of brain oscillations after sleep. Neuroimage. 2014 Nov 15;102 Pt 2:894-903.
Chang WP, Liu ME, Chang WC, Yang AC, Ku YC, Pai JT, Lin YW, Tsai SJ. Sleep apnea and the subsequent risk of breast cancer in women: a nationwide population-based cohort study. Sleep Med. 2014 Sep;15(9):1016-20.
Liang JF, Wang SJ* Hypnic headache: A review of clinical features, therapeutic options and outcomes. Cephalalgia. 2014 Sep;34(10):795-805.
Chang WP, Liu ME, Chang WC, Yang AC, Ku YC, Pai JT, Lin YW, Tsai SJ*. Sleep apnea and the subsequent risk of breast cancer in women: a nationwide population-based cohort study. Sleep Med. 2014 Sep;15(9):1016-20.
Huang CT, Chiang RP, Chen CL, Tsai YJ. Sleep deprivation aggravates median nerve injury-induced neuropathic pain and enhances microglial activation by suppressing melatonin secretion. Sleep. 2014 Sep 1;37(9):1513-23.
Wang EH, Yang AC. Pisa syndrome after discontinuation of clotiapine in a patient with intractable insomnia. J Clin Psychopharmacol. 2014 Apr;34(2):276-7.
Su VY, Liu CJ, Wang HK, Wu LA, Chang SC, Perng DW, Su WJ, Chen YM, Lin EY, Chen TJ, Chou KT*. Sleep apnea and risk of pneumonia: a nationwide population-based study. CMAJ. 2014 Apr 1;186(6):415-21.
Huang CY, Chen YT, Wu LA, Liu CJ, Chang SC, Perng DW, Chen YM, Chen TJ, Lee YC, Chou KT*. Sleep apnoea patients have higher mortality when confronting sepsis. Eur J Clin Invest. 2014 Jan;44(1):38-45.
   2013年度 研究成果
Lee YT, Tsai CF, Ouyang WC, Yang AC, Yang CH, Hwang JP*. Daytime sleepiness: a risk factor for poor social engagement among the elderly. Psychogeriatrics. 2013 Dec;13(4):213-20.
Chang WP, Liu ME, Chang WC, Yang AC, Ku YC, Pai JT, Huang HL, Tsai SJ*. Sleep apnea and the risk of dementia: A population-based 5-year follow-up study in Taiwan. PLoS One. 2013 Oct 24;8(10):e78655.
Lin YH, Ho YC, Lin SH, Yeh SH, Liu CY, Kuo TBJ, Yang CC, Yang AC* On-Call Duty Effects on Sleep-State Physiological Stability in Male Medical Interns. PLoS One. 2013 Jun 4;8(6):e65072.
Shiao TH, Liu CJ, Luo JC, Su KC, Chen YM, Chen TJ, Chou KT*, Shiao GM, Lee YC. Sleep apnea and risk of peptic ulcer bleeding: a nationwide population-based study. Am J Med. 2013 Mar;126(3):249-55.
Ko FY, Yang AC, Tsai SJ, Zhou Y, Xu LM* Physiologic and laboratory correlates of depression, anxiety, and poor sleep in liver cirrhosis. BMC Gastroenterol. 2013 Jan 22;13:18.
Chi NF, Shiao GM, Ku HL, Soong BW*. Sleep disruption in spinocerebellar ataxia type 3: a genetic and polysomnographic study. J Chin Med Assoc. 2013 Jan;76(1):25-30.
   2012年度 研究成果
Lin WC, Winkelman JW. Obstructive sleep apnea and severe mental illness: evolution and consequences. Curr Psychiatry Rep. 2012 Oct;14(5):503-10. doi: 10.1007/s11920-012-0307-6.
Chou KT, Huang CC, Tsai DC, Chen YM, Perng DW, Shiao GM, Lee YC, Leu HB*. Sleep apnea and risk of retinal vein occlusion: a nationwide population-based study of Taiwanese. Am J Ophthalmol. 2012 Jul;154(1):200-205.
Chou KT, Huang CC, Chen YM, Su KC, Shiao GM, Lee YC, Chan WL, Leu HB*. Sleep apnea and risk of deep vein thrombosis: a non-randomized, pair-matched cohort study. Am J Med. 2012 Apr;125(4):374-80.
   2011年度 研究成果
Chou KT, Chang YT, Chen YM, Su KC, Perng DW, Chang SC, Shiao GM*. The minimum period of polysomnography required to confirm a diagnosis of severe obstructive sleep apnoea. Respirology. 2011 Oct;16(7):1096-102.
Su YF, Chou KT*. Impact of sleep-disordered breathing on coagulation: the role of COPD should be clarified. Am J Respir Crit Care Med. 2011 Jun 15;183(12):1731.
Yang AC*, Tsai SJ, Yang CH, Kuo CH, Chen TJ, Hong CJ Reduced physiologic complexity is associated with poor sleep in patients with major depression and primary insomnia. J Affect Disord. 2011 Jun;131(1-3):179-85.
Chen PK, Fuh JL, Lane HY, Chiu PY, Tien HC, Wang SJ* Morning headache in habitual snorers: frequency, characteristics, predictors and impacts. Cephalalgia. 2011 May;31(7):829-36. 
Yang AC*, Yang CH, Hong CJ, Tsai SH, Kuo CH, Peng CK, Mietus JE, Goldberger AL, Thomas RJ. Sleep state instabilities in major depression: detection and quantification with an Electrocardiogram-based spectrogram method. Psychophysiology. 2011 Feb;48(2):285-291
Su YF, Chou KT*. Elevation of IL-6 solely is not sufficient to infer systemic inflammation. Chest. 2011 Jan;139(1):229-30.
   2010年度 研究成果
Chou KT, Shiao GM*. Increased morning cortisol level: effect of sleep fragmentation or stress response to the last annoying stimulus? Chest. 2010 Aug;138(2):460.
Chen PK, Fuh JL, Chen SP, Wang SJ* Association between restless legs syndrome and migraine. J Neurol Neurosurg Psychiatry. 2010 May;81(5):524-8.
   2009年度 研究成果
Shiao GM. The rapid development of sleep apnea syndrome. J Chin Med Assoc. 2009 Jun;72(6):283-4.
   2008年度 研究成果
Chen YC, Lin FC, Shiao GM, Chang SC*. Effect of rapid ascent to high altitude on autonomic cardiovascular modulation. Am J Med Sci. 2008 Sep;336(3):248-53.
Liang JF, Fuh JL, Yu HY, Hsu CY, Wang SJ* Clinical features, polysomnography and outcome in patients with hypnic headache Cephalalgia. 2008 Mar;28(3):209-15
Chang ET, Shiao GM*. Craniofacial abnormalities in Chinese patients with obstructive and positional sleep apnea. Sleep Med. 2008 May;9(4):403-10.
   1995年度 研究成果
Lu SJ, Chang SY, Shiao GM. Comparison between short-term and long-term post-operative evaluation of sleep apnoea after uvulopalatopharyngoplasty. J Laryngol Otol. 1995 Apr;109(4):308-12.